Form 14 Faq The Ten Secrets You Will Never Know About Form 14 Faq

MADISON, N.J., April 18, 2011 /PRNewswire/ — Quest Diagnostics Incorporated (NYSE: DGX), the world’s arch provider of analytic testing, advice and services, today appear the availability of its AccuType® IL28B analysis for acceptable in the anticipation of accommodating acknowledgment to peginterferon alpha-based analysis for hepatitis C virus (HCV) infection. Quest Diagnostics is now alms the analysis to physicians and added healthcare providers in the U.S. and to biologic companies for use in analytic trials research.



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 Section 14 FAQs

Section 14 FAQs | form 965 faq

The analysis was developed through a all-around non-exclusive authorization acceding beneath which Schering Corporation, a Merck affiliate, accountant assertive apparent rights claiming Interleukin (IL) 28B abiogenetic markers to Quest Diagnostics. These abiogenetic markers accept been apparent to accommodate an indicator of abeyant acknowledgment to peginterferon alpha-based analysis for HCV. Additional agreement were not disclosed.

“Our AccuType IL28B analysis will accord physicians greater insights for alleviative alone patients adulterated with the best accepted anatomy of HCV application accepted antiviral therapies,” said Rick L. Pesano, M.D., Ph.D., medical director, communicable diseases, Quest Diagnostics. “AccuType IL28B testing will additionally advice physicians accede another therapies, which in the approaching may accommodate HCV protease inhibitors.”

Combination interferon-ribavirin analysis administered over several months is advised accepted of affliction in alleviative HCV, although beginning HCV protease inhibitors are now beneath antecedence analysis by the U.S. Food and Drug Administration.(1),(2)  Side effects, such as fatigue, abasement and nausea, affect the majority of patients, and an estimated 10% to 14% of bodies abandon therapy.(3),(4) Moreover, as abounding as one in two patients abort to eradicate the virus, as adumbrated by claret tests, after a abounding advance of therapy.(5)



A certain polymorphism of the IL28B gene found in individuals adulterated with the best accepted blazon of HCV, HCV genotype 1, aids in anecdotic those patients who are alert as acceptable to annihilate the HCV virus on a abiding base back advised with pegylated interferon-ribavirin combination therapies.(6) Added factors, including age and gender, may affect analysis response.

HCV infection is the best accepted abiding claret borne infection in the United States, chronically infecting about 3.2 actor people. Left untreated, abiding HCV can advance to alarmist blight or alarmist cirrhosis acute alarmist transplantation. Abiding HCV infection accounts for an estimated 8,000 to 10,000 deaths anniversary year in the United States.(7)

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About Quest Diagnostics

Quest Diagnostics is the world’s arch provider of analytic testing, advice and casework that patients and doctors charge to accomplish bigger healthcare decisions. The aggregation offers the broadest admission to analytic testing casework through its arrangement of laboratories and accommodating account centers, and provides analytic appointment through its all-encompassing medical and accurate staff. Quest Diagnostics is a avant-garde in developing avant-garde analytic tests and avant-garde healthcare advice technology solutions that advice advance accommodating care.

Quest Diagnostics’ ample hepatitis C and B virus testing card includes hepatic action tests to advice actuate HCV acknowledgment and analyze aberrant alarmist function; Heptimax® viral RNA quantitative testing to adviser viral amount during therapy; and HCV genotyping to aid in admiration analysis continuance and success. Quest Diagnostics additionally offers tests, such as HepaScore™, to advice physicians analyze and date alarmist fibrosis.

Additional aggregation advice is accessible at www.QuestDiagnostics.com.

Quest, Quest Diagnostics, the associated logo, Nichols Institute and all associated Quest Diagnostics marks are the registered trademarks of Quest Diagnostics. All third affair marks — ®’ and ™’ — are the acreage of their corresponding owners. © 2000-2011 Quest Diagnostics Incorporated. All rights reserved.

FAQ’s | form 965 faq

(1) Merck columnist release, 1/6/11; Vertex Pharmaceuticals columnist release; 1/20/11.

(2) HCSP Fact Sheet, Hepatitis C Support Project (HCSP);2008;ver 3.

(3) Lancet 2001; 358:958-965.

(4) N Engl J Med 2002; 347:975-982.

(5) HCSP Fact Sheet, Hepatitis C Support Project (HCSP),ver 3, 12/08.

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 FAQ Tab - Home | Facebook

FAQ Tab – Home | Facebook | form 965 faq

(6) “Nature, 2009;10.1038;1-3.

(7) Hepatitis C FAQs for Health Professionals, U.S. Centers for Disease Control and Prevention Source, adapted 12/17/10.

Quest Diagnostics Contacts:Wendy Bost (Media): 973-520-2800Kathleen Valentine (Investors): 973-520-2900

SOURCE Quest Diagnostics Incorporated

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